全文获取类型
收费全文 | 294341篇 |
免费 | 17531篇 |
国内免费 | 406篇 |
专业分类
耳鼻咽喉 | 4203篇 |
儿科学 | 10265篇 |
妇产科学 | 10243篇 |
基础医学 | 44732篇 |
口腔科学 | 7484篇 |
临床医学 | 23953篇 |
内科学 | 55303篇 |
皮肤病学 | 6305篇 |
神经病学 | 20905篇 |
特种医学 | 11606篇 |
外国民族医学 | 43篇 |
外科学 | 46551篇 |
综合类 | 7737篇 |
现状与发展 | 1篇 |
一般理论 | 160篇 |
预防医学 | 19765篇 |
眼科学 | 6936篇 |
药学 | 20818篇 |
中国医学 | 739篇 |
肿瘤学 | 14529篇 |
出版年
2018年 | 3615篇 |
2017年 | 2654篇 |
2016年 | 3076篇 |
2015年 | 3486篇 |
2014年 | 4578篇 |
2013年 | 7205篇 |
2012年 | 9063篇 |
2011年 | 9442篇 |
2010年 | 6126篇 |
2009年 | 5545篇 |
2008年 | 8669篇 |
2007年 | 9514篇 |
2006年 | 9359篇 |
2005年 | 8957篇 |
2004年 | 8662篇 |
2003年 | 8149篇 |
2002年 | 7742篇 |
2001年 | 13316篇 |
2000年 | 13627篇 |
1999年 | 11348篇 |
1998年 | 2884篇 |
1997年 | 2615篇 |
1996年 | 2479篇 |
1995年 | 2538篇 |
1994年 | 2338篇 |
1992年 | 8306篇 |
1991年 | 8452篇 |
1990年 | 8261篇 |
1989年 | 8076篇 |
1988年 | 7310篇 |
1987年 | 7074篇 |
1986年 | 6719篇 |
1985年 | 6515篇 |
1984年 | 4753篇 |
1983年 | 4112篇 |
1982年 | 2458篇 |
1979年 | 4415篇 |
1978年 | 3220篇 |
1977年 | 2724篇 |
1976年 | 2495篇 |
1975年 | 2827篇 |
1974年 | 3350篇 |
1973年 | 3363篇 |
1972年 | 3115篇 |
1971年 | 2949篇 |
1970年 | 2834篇 |
1969年 | 2581篇 |
1968年 | 2537篇 |
1967年 | 2371篇 |
1966年 | 2261篇 |
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
91.
92.
93.
94.
Evidence‐ and consensus‐based (S3) Guidelines for the Treatment of Actinic Keratosis – International League of Dermatological Societies in cooperation with the European Dermatology Forum – Short version 下载免费PDF全文
R.N. Werner E. Stockfleth S.M. Connolly O. Correia R. Erdmann P. Foley A.K. Gupta A. Jacobs H. Kerl H.W. Lim G. Martin M. Paquet D.M. Pariser S. Rosumeck H.‐J. Röwert‐Huber A. Sahota O.P. Sangueza S. Shumack B. Sporbeck N.A. Swanson L. Torezan A. Nast 《Journal of the European Academy of Dermatology and Venereology》2015,29(11):2069-2079
95.
96.
D Hernaus D Collip Z Kasanova O Winz A Heinzel T van Amelsvoort S M Shali J Booij Y Rong M Piel J Pruessner F M Mottaghy I Myin-Germeys 《Translational psychiatry》2015,5(4):e547
Stress is an important risk factor in the etiology of psychotic disorder. Preclinical work has shown that stress primarily increases dopamine (DA) transmission in the frontal cortex. Given that DA-mediated hypofrontality is hypothesized to be a cardinal feature of psychotic disorder, stress-related extrastriatal DA release may be altered in psychotic disorder. Here we quantified for the first time stress-induced extrastriatal DA release and the spatial extent of extrastriatal DA release in individuals with non-affective psychotic disorder (NAPD). Twelve healthy volunteers (HV) and 12 matched drug-free NAPD patients underwent a single infusion [18F]fallypride positron emission tomography scan during which they completed the control and stress condition of the Montreal Imaging Stress Task. HV and NAPD did not differ in stress-induced [18F]fallypride displacement and the spatial extent of stress-induced [18F]fallypride displacement in medial prefrontal cortex (mPFC) and temporal cortex (TC). In the whole sample, the spatial extent of stress-induced radioligand displacement in right ventro-mPFC, but not dorso-mPFC or TC, was positively associated with task-induced subjective stress. Psychotic symptoms during the scan or negative, positive and general subscales of the Positive and Negative Syndrome Scale were not associated with stress-induced [18F]fallypride displacement nor the spatial extent of stress-induced [18F]fallypride displacement in NAPD. Our results do not offer evidence for altered stress-induced extrastriatal DA signaling in NAPD, nor altered functional relevance. The implications of these findings for the role of the DA system in NAPD and stress processing are discussed. 相似文献
97.
98.
Niall P McGoldrick Eabhann M O’Connor Nikos Davarinos Rose Galvin John F Quinlan 《World journal of orthopedics》2015,6(11):977-982
AIM: To examine the cost benefit conferred by the perioperative administration of intravenous tranexamic acid (TXA) in lower limb arthroplasty.METHODS: This study evaluates the use of TXA in 200 consecutive lower limb arthroplasties performed in a single surgeon series. The initial 100 patients (control group) underwent surgery without perioperative administration of TXA while the subsequent 100 patients (TXA group) all received 1 g TXA at the time of induction of anaesthesia. Pre- and post-operative haemoglobin, platelet count, haematocrit, the use of blood product post-operatively, length of stay were examined. A financial analysis of both groups was then undertaken.RESULTS: The mean age of patients in both groups was 63 ± 13 years. There were no significant differences between groups in terms of gender (P = 0.47), proportion of total hip replacement to total knee replacement (P = 0.25) or pre-operative haemoglobin (P = 0.43). In the control group, the transfusion rate was 22%. In the TXA group, the transfusion rate dropped to 2% (P < 0.001). The mean post-operative haemoglobin was 10.82 ± 1.55 g/dL in the control group vs 11.33 ± 1.27 g/dL in the TXA group (P = 0.01). The total cost of transfused blood products was €11055 and €603 respectively. The mean length of stay in the control group was 6.53 ± 5.93 d vs 5.47 ± 4.26 d in the TXA group (P = 0.15) leading to an estimated financial saving of €114586. There was one pulmonary embolus in the control group and one deep venous thrombosis in the TXA group.CONCLUSION: Intravenous TXA reduces blood loss in lower limb arthroplasty. This leads to lower transfusion rates, shorter length of stay in hospital and significant financial savings. 相似文献
99.
100.